Brief entry

Chlordiazepoxide

Anxiety and sleep · Mechanism, prescribing context, monitoring and product information.

Reference information · Brief entry
Last content update
2026-10-26
Clinical review
Not independently reviewed
Source jurisdiction
See individual sources
Coverage
Brief entry
What changed in this edition

Clinical context #

Benzodiazepine with active metabolites. Withdrawal and anxiety indications require separate clinical protocols and dose references.

Condition-specific prescribing #

Indication-specific records shared with the clinical handbook. Population, formulation and source jurisdiction are part of each regimen.

Prescribing reference

Chlordiazepoxide

Supervised alcohol withdrawal: ASAM sample symptom-triggered regimen

Adults · Oral capsules/tablets · Oral · US ASAM supervised protocol example; not an Indian product-label claim.

Starting dose
ASAM example: 25–100 mg orally when CIWA-Ar is ≥10; clinical severity and vulnerability determine the selected dose.
Titration
Example interval every 4–6 hours, with reassessment and additional doses only under the supervising protocol.
Treatment range / target
25–100 mg per administration in this sample schedule.
Maximum / limits
No universal daily maximum is defined by this sample; escalating need or oversedation requires senior review, not unrestricted repeat dosing.
Trial & duration
Acute withdrawal only; fixed-dose examples taper over 3–5 days.
Monitoring
Trained observation of symptoms, alertness and respiration; reassess before dosing.
Population & organ-function adjustments
Reduce exposure or choose an alternative when hepatic impairment or frailty increases accumulation risk.
Important cautions
Not a home self-dosing schedule. CIWA-Ar is unsuitable for directing doses in delirium or unreliable communication.

Open the condition treatment guide ↗

Special populations & counseling #

Age, renal and hepatic function, pregnancy, breastfeeding, co-medication and the treatment indication require medicine-specific review. A general class statement cannot establish suitability for an individual.

Discuss the intended benefit, expected review plan, relevant adverse effects, driving or falls considerations, and how to obtain help. Stopping, switching or restarting requires the exact product’s instructions and clinical assessment.

Brands & products #

Supplied catalogue observations; price dates may be unknown. Presence does not establish current stock or Indian approval.

Reference coverage #

Ingredient profiles and product records are separate. Details not supplied in this reference must be checked in the exact product information; missing information is not evidence of absence or safety.

References · 4
  1. ASAM alcohol withdrawal guideline · United States · Checked 2026-10-26 · Supports: Chlordiazepoxide — Supervised alcohol withdrawal: ASAM sample symptom-triggered regimen (Oral capsules/tablets)
  2. DailyMed structured product information · Retrieved 2026-10-07
  3. MHRA product information · Retrieved 2026-10-07
  4. CDSCO approved new drugs · Retrieved 2026-10-07

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