Olanzapine

Indications & formulation #

Schizophrenia in adults. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral tablet · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

Start 5–10 mg/day; usual initial target 10 mg/day. Further 5 mg adjustments generally occur at least weekly; doses above 20 mg/day are not indicated in this label.

Contraindications & important cautions #

Monitor weight, glucose, lipids, orthostasis and anticholinergic effects. Dementia-related psychosis carries excess mortality risk.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Weight/metabolic changes, sedation, anticholinergic effects and orthostasis can impair function.

Interactions #

Smoking changes and CYP1A2 modifiers can alter exposure. Oral and injectable instructions differ.

Monitoring #

Review weight, glucose/lipids, blood pressure, movement findings and function. Assess dementia-related cautions where relevant.

Special populations #

Older/debilitated patients or slower metabolism may warrant a 5 mg start. Smoking cessation can increase exposure.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

Plan supervised reduction with relapse monitoring; injectable products require separate instructions.

Brands & products #

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.